Functional and cognitive impairment, social environment, frailty and adverse health outcomes in older patients with head and neck cancer, a systematic review

With population ageing there will be an increasing number of older patients with cancer. This trend can also be observed in the patient population presenting with head and neck cancer. In the USA, it is estimated that between 2010 and 2030 the incidence of oral cavity and pharyngeal cancer in people aged 65years and over will approximately increase from 19,000 patients in 2010 to 31,000 patients in 2030. This would be an increase with more than 60% [1]. Older patients are very heterogenic with respect to functional capacity, cognitive functioning, mobility and frailty, therefore it remains challenging to identify older patients who are at highest risk for adverse health outcomes such as delirium, side-effects, prolonged length of hospital stay, reduced quality of life or mortality.

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