Prevalence and management of Recurrent Respiratory Papillomatosis (RRP) in the UK: cross sectional study

Abstract

Objectives

To estimate the number of patients with recurrent respiratory papillomatosis (RRP) currently managed in secondary and tertiary health care in the UK and the frequency of its treatment with Coblation^™.

Design

Cross-sectional survey of ENT consultants in the UK with validation using Hospital Episode Statistics (HES) inpatient data

Setting

Online survey.

Participants

ENT consultants in the UK

Main outcome measures

Number of RRP patients currently managed in acute care in the UK and frequency of use of Coblation.

Results

283 ENT consultants from 128 UK NHS healthcare trusts and health boards completed the online survey. Responses were received from 86% of surveyed organisations, and an estimated 45% of all ENT consultants in UK. The estimated number of RRP patients from the cross-sectional survey was 918 (at August 2015) which included 730 patients in England. The number of RRP patients in England estimated from HES (2014/15 financial year) was up to 741. A total of 42 Coblation procedures conducted in the UK were identified from the cross-sectional survey; 36 were conducted in England compared with 34 identified from HES.

Conclusions

The numbers of RRP patients and Coblation procedures identified in England from a cross-sectional survey and HES were in broad agreement. Our study estimated 1.42 RRP patients per 100,000 in the general UK population. We also estimated that Coblation procedures accounted for 3% of interventional treatments conducted in the UK RRP population.

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