Large diameter fully covered self-expanding metal stent placement for palliation of proximal malignant esophageal strictures.

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Large diameter fully covered self-expanding metal stent placement for palliation of proximal malignant esophageal strictures.

Dis Esophagus. 2015 Aug-Sep;28(6):579-84

Authors: Bassi M, Luigiano C, Fabbri C, Ferrara F, Ghersi S, Alibrandi A, Fuccio L, Virgilio C, Patelli M, Zanello M, Cennamo V

Abstract
In patients with malignant esophageal strictures within 6 cm from the upper esophageal sphincter, self-expanding metal stents placement represents a challenge because there is an increased risk of complications. The aim of this study was to assess the safety and effectiveness of large-diameter WallFlex(®) fully covered self-expanding metal stents for palliation of patients with proximal malignant esophageal strictures. From March 2010 to December 2012, 12 patients with proximal strictures (4-6 cm from the upper esophageal sphincter) and six with very proximal strictures (<4 cm from the upper esophageal sphincter) were palliated with this fully covered self-expanding metal stent and included in the study. Technical success was 100% and clinical success was 94%. The mean baseline dysphagia score was 3.2, and 1 week after stenting it improved significantly to 1.3 (P < 0.001). Early complications occurred in four patients, more frequently in patients with very proximal strictures as compared with patients with proximal strictures (P = 0.02). Late complications occurred in five patients, and there were no differences between patients with very proximal strictures or proximal strictures (P = 0.245). The mean survival after stent placement was 119 days, and no differences between patients with very proximal strictures versus proximal strictures were found (P = 0.851). There was no stent-related mortality or 30-day mortality. Our results suggested that a large-diameter fully covered self-expanding metal stent is an effective and secure device for palliation of patients with proximal malignant esophageal strictures.

PMID: 24827641 [PubMed - indexed for MEDLINE]

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