Oxcarbazepine induced toxic epidermal necrolysis - a rare case report.

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Oxcarbazepine induced toxic epidermal necrolysis - a rare case report.

Indian J Pharmacol. 2015 Jul-Aug;47(4):459-61

Authors: Guleria VS, Sharda C, Rana T, Sood AK

Abstract
Carbamazepine, is well known to cause Stevens-Johnson syndrome and toxic epidermal necrolysis(TEN). Oxcarbazepine, a 10-keto analog of carbamazepine, is an anticholinergic, anticonvulsant and mood stabilizing drug, used primarily in the treatment of epilepsy. Its efficacy is similar to carbamazepine but allergic reactions and enzyme induction is low. We describe a case of oxcarbazepine induced TEN, who presented with erythematous ulcerative maculopapular rash.

PMID: 26288485 [PubMed - indexed for MEDLINE]

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