Hypoglossal nerve palsy: 245 Cases.

Hypoglossal nerve palsy: 245 Cases.

Muscle Nerve. 2016 May 23;

Authors: Stino AM, Smith BE, Temkit M, Nagi Reddy S

Abstract
INTRODUCTION: Apart from a case series of 100 subjects in 1996 and several small cohorts, there are no large retrospective series of cranial nerve XII (CN XII) palsy.
METHODS: From 1984 to 2014, 245 cases of CN XII palsy were identified via retrospective chart review using historical and exam findings that confirmed the diagnosis. In addition to clinical characteristics, univariate and multivariate models were investigated to predict neoplastic CN XII palsy.
RESULTS: Major etiologic categories included: postoperative (29.3%), idiopathic (15.1%), primary neoplastic (14.2%), metastatic malignancy (13.0%), inflammatory (7.3%), radiation (6.1%), and traumatic (4.1%). A multivariate model revealed male gender and a personal history of cancer as predictive of neoplastic CN XII palsy.
CONCLUSIONS: The most frequent etiologies and disease categories of CN XII palsy were identified, and male gender and personal history of cancer were found to be predictive of a neoplastic cause of CN XII palsy. This article is protected by copyright. All rights reserved.

PMID: 27214783 [PubMed - as supplied by publisher]

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