[Gastro-esophageal Reflux Disease and malignant progression--equal risk for men and women?].

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[Gastro-esophageal Reflux Disease and malignant progression--equal risk for men and women?].

Z Gastroenterol. 2015 Aug;53(8):779-81

Authors: Pech O

Abstract
Gastroesophageal reflux disease (GERD) is highly prevalent in the Western world. Patients with GERD have a 10 fold increased risk to develop a Barrett's esophagus. Patients with Barrett's esophagus have a higher risk for an esophageal adenocarcinoma. Men have more severe reflux with a higher grade of inflammation and acid reflux. This seems to be the reason why men develop a Barrett's esophagus more frequently--the risk is approximately 2 to 3 fold and the risk for an esophageal adenocarcinoma is even 3 to 6 times higher.

PMID: 26284325 [PubMed - indexed for MEDLINE]

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