Atypical antipsychotics for insomnia: a systematic review

• Despite limited evidence, quetiapine is commonly used for insomnia• A systematic, comprehensive search revealed one small randomized, controlled trial of quetiapine for primary insomnia• This paper resolves uncertainty in the evidence base that was present in previous non-systematic reviews• There is a lack of evidence for using atypical antipsychotics for insomnia

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