Surgical treatment For T4 Oropharyngeal Cancer

To the Editor The article by Zenga et al on the role of surgery for T4 oropharyngeal cancer was interesting, but I believe it had several omissions that add to the limitations. The most problematic issue with the analysis was the inherent bias in a comparison between 2 groups, 1 that undergoes the therapy (surgery) and 1 that does not, when the latter group has patients who either medically or technically cannot receive the therapy.

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