Τρίτη 30 Αυγούστου 2016

Gastric pull-up reconstruction after treatment for advanced hypopharyngeal and cervical esophageal cancer

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Publication date: Available online 29 August 2016
Source:European Annals of Otorhinolaryngology, Head and Neck Diseases
Author(s): Y. Marion, G. Lebreton, C. Brévart, T. Sarcher, A. Alves, E. Babin
ObjectivesIn advanced hypopharyngeal and cervical esophageal carcinoma, the choice of reconstruction technique after total circumferential pharyngolaryngectomy (TCPL) remains controversial. We studied results of digestive tract reconstruction using gastric pull-up, concomitant or secondary to TCPL or after failure of reconstruction.Material and methodsTwenty-four patients treated by gastric pull-up after TCPL for advanced hypopharyngeal or cervical esophageal carcinoma between December 1998 and January 2011 were retrospectively reviewed.ResultsTwo-year survival was 37.5% (n=9). Thirty-day mortality was 4.1% (n=1), but 3 more patients died before discharge. Perioperative morbidity was 54.1% (n=13), including 9 fistulas (37.5%). Seventeen patients (71%) recovered oral feeding.ConclusionGastric pull-up is an interesting reconstruction technique after TCPL with invasion of the esophageal mouth, allowing comfortable oral feeding, but with non-negligible morbidity and mortality. Long-term survival is not high, partly due to the unfavorable prognosis of advanced hypopharyngeal and cervical esophageal tumor. The present high rate of fistula raises doubts for this surgery as second-line reconstruction after primary failure.



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