Quantitative body mass characterization before and after head and neck cancer radiotherapy: A challenge of height-weight formulae using computed tomography measurement

Patients with head and neck cancer (HNC) commonly experience major weight loss, both prior to and during therapy, which is associated with poor functional and survival outcomes. Weight loss in cancer patients result from both cancer-associated metabolic states, as well as cancer treatment toxicity sequelae. For HNC, the latter are especially pronounced, and include mucositis, xerostomia, dysphagia and nausea/vomiting. These symptoms can lead to poor oral intake and weight loss, with a resultant change in body composition.

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