Sleep disordered breathing and nocturnal hypoxemia in young adults with sickle cell disease

• An AHI > 5 was seen in 10 of 20 subjects attending a sickle cell disease clinic.• Elevated AHI correlated with systolic BP, mitral valve E/A ratio, and QoL scores.• Hypoxemia occurred in some subjects independently from sleep apnea events.• Results suggest further study with larger subject numbers is warranted.

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