Τετάρτη 29 Ιουνίου 2016

Constipation, fiber intake and incompliance contribute to inadequate colonoscopy bowel preparation: A prospective cohort study

Abstract

Background

Adequate bowel preparation is important for colonoscopy. Currently available evidence on the determinants of poor bowel preparation has largely emanated from studies conducted in western countries. We sought to identify risk factors for inadequate bowel preparation for colonoscopy in the Chinese population.

Methods

In this single-center study, patients who attended the out-patient department between March 2013 and December 2014, and had indications for colonoscopy, were prospectively enrolled. Questionnaires were administered to the patients. Demographic, clinical characteristics and Procedure-related parameters such as procedure time were recorded. Bowel preparation was assessed using Boston bowel preparation scale (BBPS) score.

Results

A total of 409 patients (mean age: 48.8 ± 12.9 years) of whom 61% were male participated in the study. On univariate analysis, poor educational status (P = 0.020), chronic constipation (P = 0.001), no physical exercises after medication (P < 0.001), high fiber diet during the 24 h period immediately preceding the colonoscopy (P < 0.001), incomplete intake of preparation (P < 0.001), passage of yellow or dark stools before colonoscopy (P < 0.001), waiting time (P = 0.001) and stool frequency after medication (P = 0.048) were associated with inadequate bowel preparation. On multivariate analysis, chronic constipation (Odds Ratio [OR] 2.05; 95% Confidence Interval [CI], 1.31-3.23), incomplete intake of the preparation (OR 2.77; 95% CI, 1.47-5.21) and high fiber diet (OR 2.15; 95% CI, 1.40-3.28) were independent risk factors for inadequate bowel preparation.

Conclusion

Chronic constipation, poor compliance with treatment and high fiber diet were predictors of poor bowel preparation. Patients with these risk factors require more effective strategies for bowel preparation.



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