Evaluation of antireflux surgery using multichannel intraluminal impedance-pH measurement in neurologically impaired patients.

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Evaluation of antireflux surgery using multichannel intraluminal impedance-pH measurement in neurologically impaired patients.

Pediatr Surg Int. 2015 Oct;31(10):911-6

Authors: Tanaka A, Shimono R, Kubo H, Fujii T, Miyatake N

Abstract
PURPOSE: This study aimed to evaluate esophageal function before and after antireflux surgery (ARS) in neurologically impaired (NI) patients using 24 h multichannel intraluminal impedance (MII)-pH measurement.
METHODS: Seven NI patients (age, 0-33 years; median, 13 years) were assessed before and after ARS using 24 h MII-pH. We described reflux parameters such as pH reflux index, bolus exposure index, number of acidic and nonacidic reflux episodes, mean acid clearance time and median bolus clearance time, and esophageal motility parameters in dry swallows such as bolus presence time (BPT), total bolus transit time (TBTT), and total propagation velocity (TPV).
RESULTS: The postoperative reflux parameters such as pH reflux index, acid clearance time, bolus exposure index, and the number of acidic reflux episodes significantly decreased (P < 0.05) compared with the preoperative ones. The esophageal motility parameters including all sites of BPTs, TBTT, and TPV did not change in the MII-pH measurement after ARS (P = non-significant).
CONCLUSION: ARS effectively reduced gastro-esophageal reflux (GER) in NI patients without the impairment of esophageal motility by MII-pH measurement. MII-pH was useful to detect the subtype of GER before and after ARS and appeared to be appropriate for evaluating esophageal motility.

PMID: 26285892 [PubMed - indexed for MEDLINE]

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