Brain iron deficiency in idiopathic restless legs syndrome measured by quantitative magnetic susceptibility at 7 tesla

• 7T QSM reveals brain iron deficiency in idiopathic RLS patients off treatment• RLS patients showed decreased iron in thalamus and dentate nucleus• Decreased iron in the SN correlated with increased PLMS for RLS• Iron deficiency in SN was observed in RLS with severe PLMS

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