The A2DS2 Score as a Predictor of Pneumonia and In-Hospital Death after Acute Ischemic Stroke in Chinese Populations

Background and Purpose

Stroke-associated pneumonia (SAP) is a common complication and an important cause of death during hospitalization. The A²DS² (Age, Atrial fibrillation, Dysphagia, Sex, Stroke Severity) score was developed from the Berlin Stroke Registry and showed good predictive value for predicting SAP. We sought to identify the association between the A²DS² score and SAP, and, furthermore, to identify whether the A²DS² score was a predictor for in-hospital death after acute ischemic stroke in a Chinese population.

Methods

This was a retrospective study. 1239 acute ischemic stroke patients were classified to low A²DS² group (0â€"4) and high A²DS² score (5â€"10) group. Primary outcome was in-hospital SAP. Logistic regression analyses were performed to identify the association between the A²DS² score and SAP, and also the association between the A²DS² score and in-hospital death.

Results

The overall incidence rates of SAP and in-hospital mortality after acute ischemic stroke were 7.3% and 2.4%, respectively. The incidence rate of SAP in low and high A²DS² score groups was separately 3.3% and 24.7% (P Conclusions

The A²DS² score was a strong predictor for SAP and in-hospital death of Chinese acute ischemic stroke patients. The A²DS² score might be a useful tool for the identification of patients with a high risk of SAP and death during hospitalization.

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