Human milk oligosaccharides and development of cow’s milk allergy in infants

Publication date: Available online 1 October 2016
Source:Journal of Allergy and Clinical Immunology
Author(s): Antti E. Seppo, Chloe A. Autran, Lars Bode, Kirsi M. Järvinen
Human milk oligosaccharides (HMOs) provide a main substrate to help shape the infant's gut microbiota and affect the maturation of the intestinal mucosal immune system. In our cohort, infants that received human milk with low Lacto-N-fucopentaose (LNFP) III concentrations (< 60μM) were more likely to become affected with cow's milk allergy when compared to high LNFP III-containing milk (odds ratio 6.7, 95% CI 2.0-22).



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