Somatosensory temporal discrimination threshold in Parkinson’s disease parallels disease severity and duration

The somatosensory temporal discrimination threshold (STDT) is defined as the shortest time interval at which an individual recognizes a pair of stimuli as separate in time (Lacruz et al., 1991). It relies on a purely sensory process that allows the brain to "filter" the relevant sensory information from external sources (Costa et al., 2008). Previous studies on healthy subjects have suggested that the STDT depends on the integrity of a complex cortico-subcortical network in which S1 plays an encoding role and basal ganglia determine a time-related interaction between cortical and subcortical structures (Conte et al., 2012; Harrington et al., 1998a, 1998b; Ivry, 1996).

from #ORL via xlomafota13 on Inoreader http://ift.tt/29Mp1cw
via IFTTT