Hyperarousal in insomnia and hypnotic dose escalation

• not all people with insomnia are hyperaroused as shown by MSLT.• hyperarousal in insomnia as defined by MSLT is also seen in elevation of daytime NE. 3) Hi daytime MSLT/NE is associated with enhanced risk of hypnotic dose escalation.• the dose escalation is expressed primarily in insomniacs receiving placebo.

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