Molecular characterization and pathogenicity determination of hypervirulent Klebsiella pneumoniae clinical isolates serotype K2 in Mexico

Publication date: Available online 31 January 2019

Source: Diagnostic Microbiology and Infectious Disease

Author(s): Catalán-Nájera Juan Carlos, Barrios-Camacho Humberto, Duran-Bedolla Josefina, Sagal-Prado Alan, Hernández-Castro Rigoberto, Jorge García-Méndez, Morfín-Otero Rayo, Velázquez-Larios María del Rosario, Ortíz-Navarrete Vianney, Gutierrez-Xicotencatl Lourdes, Alpuche-Aranda Celia, Silva-Sánchez Jesús, Garza-Ramos Ulises

Abstract

Hypervirulent Klebsiella pneumoniae have been rarely described in Latin America. This work describes the characterization of hypervirulent K. pneumoniae isolates capsular serotype K2 belonging to sequence types 86 and 380. The assays showed the hypervirulent K. pneumoniae highly virulent, which is determined by the plasmid borne virulence-genes. At this time, the hypervirulent K. pneumoniae clinical isolates in Mexico are extensively susceptible to antibiotics.

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