Extensive bony metastases from facial metatypical basal cell carcinoma: a case report

Publication date: Available online 28 December 2018

Source: British Journal of Oral and Maxillofacial Surgery

Author(s): A. Pabst, M. Klinghuber, G. Müller, S. Vandersee, R. Werkmeister

Abstract

Metastatic basal cell carcinoma (BCC) is rare. We treated a 44-year-old woman with an extended facial metatypical BCC in whom staging showed no local or distant metastases, but one year after resection, we diagnosed a local recurrence. Re-staging, using a fludeoxyglucose positron emission tomography-computed tomogram, (FDG PET-CT) showed suspected accumulations of FDG in the whole axial skeleton. Bone punch biopsy examination confirmed extensive bony metastases, and after resection of the relapse, we began her on a systemic treatment with a Hedgehog-pathway inhibitor (vismodegib), which resulted in partial remission.

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