Intranasal tissue necrosis associated with opioid abuse: Case report and systematic review

ConclusionIntranasal opioid abuse is a prevalent condition associated with chronic pain and tissue necrosis that is clinically concerning for invasive fungal disease. Whereas IFRS must be excluded, even in patients without known immunodeficiency, complete resolution of symptoms can be expected following surgical debridement with cessation of opioid abuse. Laryngoscope, 2017 (Source: The Laryngoscope)

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