Parkinson's disease (PD) is a basal ganglia disorder that results in general slowness of movement and an effective treatment option consists in subthalamic deep brain stimulation (DBS). Postoperatively, DBS-electrodes are externalized which gives the unique opportunity of recording local field potentials (LFP). Previous studies have shown that there are disease specific oscillatory patterns at rest, most prominently an increased β synchronization (Kühn, 2006) that correlates with clinical symptoms of PD such as rigidity and bradykinesia (Neumann, 2016).
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OtoRhinoLaryngology by Alexandros G.Sfakianakis,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174
Σάββατο 30 Σεπτεμβρίου 2017
P 75 Movement-induced γ oscillations in the subthalamic nucleus are increased by dopamine and scaled by velocity in patients with Parkinson’s disease
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