Σάββατο 2 Ιουλίου 2016

A very unusual cause of dysphagia: mantle cell lymphoma.

A very unusual cause of dysphagia: mantle cell lymphoma.

Ann Gastroenterol. 2016 Jul-Sep;29(3):383-5

Authors: Zullo A, Cerro P, Chios A, Andriani A, Balsamo G, Francesco VD, Bruzzese V

Abstract
Dysphagia is an alarm symptom requiring a prompt investigation. Different benign and malignant diseases may present such a symptom. We describe a case of a 79-year-old patient who complained of fluctuating dysphagia episodes following solid food ingestion in the previous 5 months with mild weight loss. No other gastrointestinal symptoms were present. The patient was referred by the General Practitioner for a videofluoroscopic swallow examination which revealed nodularity of mucosa surface in the oropharynx, esophagus, fundus, and gastric body. Upper endoscopy confirmed the feature, also showing a normal mucosa of the antrum and duodenum. The histological examination revealed a mantle cell lymphoma (MCL). A stage III, MCL involving the esophagus and proximal stomach was eventually diagnosed. Esophageal MCL localization is extremely rare, and this is the first report showing a clinical onset with dysphagia.

PMID: 27366047 [PubMed]



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