Neck metastasis of a juvenile granulosa cell tumour. A case report and literature review

Publication date: March 2016
Source:Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 17, Issue 1
Author(s): M. Al Khalil, J. Joshi Otero, I. Mujeeb, M. Riyas
Juvenile granulosa cell tumour (JGCT) is a rare tumour arising from the ovarian sex cord stroma (SCST) and comprising about 5 percent of all granulosa cell tumours. To our knowledge, a cervical metastasis has not been described before.We report a case of a 19-year-old female who had a left supraclavicular mass with a previous history of a JGCT in 2010 and an abdominal recurrence in 2011 followed by radiotherapy and chemotherapy after surgery.JGCT generally affects young women, can be hormonally active, and has malignant potential. The diagnosis is made by histopathology after surgical removal, although it should be suspected when there is a large adnexal tumour along with hyperestrogenism signs. Regional lymph nodes metastases are rare let alone extra-abdominal ones.



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