Generating Recombinant Vesicular Stomatitis Viruses for Use as Vaccine Platforms.

Related Articles

Generating Recombinant Vesicular Stomatitis Viruses for Use as Vaccine Platforms.

Methods Mol Biol. 2017;1581:203-222

Authors: Ruedas JB, Connor JH

Abstract
The unique properties of vesicular stomatitis virus (VSV) make it a promising vaccine platform. With the advent of plasmid-based approaches to generate recombinant VSV viruses that express glycoproteins of other viruses, researchers now have the means to generate vaccine candidates targeting a variety of human pathogens. This chapter gives a general overview of the workings of VSV as a vaccine platform and provides a detailed protocol for the generation of recombinant VSV from plasmids.

PMID: 28374251 [PubMed - in process]

from #ORL via xlomafota13 on Inoreader http://ift.tt/2oHMK4z
via IFTTT